ea0019p276 | Pituitary | SFEBES2009
Al-Ali N
, Halsall D
, Antoun N
, Pickard J
, Wood D
, Simpson H
, Jennings A
, Chatterjee K
, Gurnell M
Introduction: Thyrotropinomas comprise <1% of all pituitary tumours, but detection is increasing with more widespread use of ultrasensitive TSH assays. Although distinct, the classical biochemical signature hyperthyroxinaemia with non-suppressed TSH is not specific to thyrotropinoma, as drug effects, non-thyroidal illness, and assay interference can all yield similar patterns of thyroid function tests. Even when these more common confounders have been exclude...